Flux continu

Le nombre de cancers chez les enfants explose, mais il serait possible de contenir ce phénomène, explique la toxicologue Laurence Huc dans cet entretien. Cette augmentation est largement liée aux pesticides et aux substances chimiques présentes dans notre environnement.

Chronic exposure to pesticide mixtures through diet is common, yet their combined metabolic effects and interactions with dietary factors remain unclear. We identified four pesticides prevalent in human exposure (imazalil, thiabendazole, boscalid, lambda-cyhalothrin) and assessed their combined impacts on hepatic metabolism and metabolic homeostasis using human liver cells and male mice fed standard chow or western diets. We found that the pesticide mixture induced metabolic perturbations in human hepatocytes. In addition, the pesticide mixture altered hepatic gene expression in chow-fed mice and exacerbated western diet-induced glucose intolerance, fasting hyperglycemia, and insulin resistance without affecting body weight or liver steatosis. These findings reveal that dietary context influences the metabolic consequences of pesticide mixtures, highlighting the need to consider nutritional status when evaluating environmental contaminant risks. Our results suggest that pesticide mixtures at reference doses m

Exclusive: Federal government court filings claim internal company documents included warnings about products being toxic

Née dans les années 1960, l’écotoxicologie doit aujourd’hui s’adapter et évoluer face aux nouveaux défis environnementaux.

According to the Associated Press, the Trump administration last week proposed a set of rollbacks that would decimate the country’s waterways. Legally, Trump can’t just undo the Biden-era rules on a whim. Instead, his EPA has started work on a convoluted workaround, which includes state-level enforcement delays and revisions to the original regulations.

La pollution des sols par les métaux toxiques est omniprésente, mais sa répartition mondiale restait inconnue. Des chercheurs ont analysé une base de données mondiale sur la pollution des sols par l'arsenic, le cadmium, le cobalt, le chrome, le cuivre, le nickel et le plomb, à partir de 796 084 points d'échantillonnage issus de 1 493 études régionales. Grâce à des techniques d'apprentissage automatique, ils ont cartographié les zones où les seuils sanitaires et agricoles sont dépassés. Les résultats révèlent l'existence, jusqu'alors insoupçonnée, d'une zone à haut risque et enrichie en métaux dans les basses latitudes d'Eurasie, attribuée à des facteurs climatiques, topographiques et anthropiques importants. Cette zone peut être considérée comme un indicateur de l'ère de l'Anthropocène.

Millions of Pages of Previously Classified Documents on Industrial Poisons (and Counting)

Together with the Center for International Environmental Law, we expose the scientific deception by chemicals industry which is delaying or derailing regulation to protect health and the environment.

There is mounting experimental evidence that lifetime exposure to increasing atmospheric CO2 levels can negatively impact the normal physiology of organisms. Directly assessing this in humans is very difficult. We analysed serum bicarbonate (HCO3−), calcium (Ca) and phosphorus (P) from 1999 to 2020 as indirect proxies for atmospheric CO2 exposure. Over this period, average bicarbonate levels in this population show an increasing trend which parallels rising atmospheric CO2 concentrations. Both. If these trends continue, blood bicarbonate values could be at the limit of the accepted healthy range in half a century, and Ca and P will be at the limit of their healthy ranges by the end of this century. This has the potential to cause a range of adverse health effects.

Residents report terror of smoke-filled city, from potentially toxic rain, air and water to food scarcity and difficulty of escape