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We propose a new paradigm, as toxicology currently lacks the proper perspective. From the 1950s to the 1970s, at least one-third of all toxicological testing in the United States, including for chemicals and drugs, was misleading scientists, and this worldwide issue persists today. Moreover, petroleum-based waste and heavy metals have been discovered in pesticide and plasticizer formulations. These contaminations have now reached all forms of life. Widespread exposure to chemical mixtures promotes health and environmental risks. We discovered that pesticides have never undergone long-term testing on mammals in their full commercial formulations by regulatory authorities or the pesticide industry; instead, only their declared active ingredients have been assessed, contrary to environmental law recommendations. The ingredients of these formulations are not fully disclosed, yet the formulations are in general at least 1000 times more toxic at low environmentally relevant doses than the active ingredients alone u

22 of the planet’s 34 vital signs are at record levels, with many of them continuing to trend sharply in the wrong direction. This is the message of the sixth issue of the annual “State of the climate” report. The report was prepared by an international coalition with contribution from the Potsdam Institute for Climate Impact Research (PIK) and led by Oregon State University scientists. Published today in BioScience, it cites global data from the Intergovernmental Panel on Climate Change (IPCC) in proposing “high-impact” strategies.

Four key parts of the Earth’s climate system are destabilising, according to a new study with contributions from the Potsdam Institute for Climate Impact Research (PIK). Researchers analysed the interconnections of four major tipping elements: the Greenland ice sheet, the Atlantic meridional overturning circulation (AMOC), the Amazon rainforest and the South American monsoon system. All four show signs of diminished resilience, raising the risk of abrupt and potentially irreversible changes.

The Atlantic meridional overturning circulation (AMOC) is an important tipping element in the climate system. There is a large uncertainty whether the AMOC will start to collapse during the century under future climate change, as this requires long climate model simulations which are not always available. Here, we analyze targeted climate model simulations done with the Community Earth System Model (CESM) with the aim to develop a physics-based indicator for the onset of an AMOC tipping event. This indicator is diagnosed from the surface buoyancy fluxes over the North Atlantic Ocean and is performing successfully under quasi-equilibrium freshwater forcing, freshwater pulse forcing, climate change scenarios, and for different climate models. An analysis consisting of 25 different climate models shows that the AMOC could begin to collapse by 2063 (from 2026 to 2095, to percentiles) under an intermediate emission scenario (SSP2-4.5), or by 2055 (from 2023 to 2076, to percentiles) under a high-end emission scenar

This article examines the technocentric bias that characterizes climate mitigation literature, focusing on the reports of the IPCC's Working Group III. This bias stems from structural features of the scientific field that prioritizes innovation, leading to the overrepresentation of technological solutions in climate research. Funding mechanisms further reinforce this tendency by incentivizing collaboration with industrial R&D, creating a self-reinforcing loop in which scientific authority and industrial interests converge. The IPCC's institutional positioning—as a policy-relevant yet politically cautious body—amplifies this dynamic by favoring allegedly “cost-effective” technological pathways that lack practical feasibility.

There is rising concern that several parts of the Earth system may abruptly transition to alternative stable states in response to anthropogenic climate and land-use change. Key candidates of such tipping elements include the Greenland Ice Sheet, the Atlantic Meridional Overturning Circulation, the South American monsoon system and the Amazon rainforest. Owing to the complex dynamics and feedbacks between them via oceanic and atmospheric coupling, the levels of anthropogenic forcing at which transitions to alternative states can be expected remain uncertain. Here we demonstrate how such interactions can generate spurious signals and potentially mask genuine signs of destabilization. We further review and present observation-based evidence that the stability of these four tipping elements has declined in recent decades, suggesting that they have moved towards their critical thresholds, which may be crossed within the range of unmitigated anthropogenic warming. Our results call for better monitoring of these ti

The White House has instructed NASA employees to terminate two major, climate change-focused satellite missions. As NPR reports, Trump officials reached out to the space agency to draw up plans for terminating the two missions, called the Orbiting Carbon Observatories. They've been collecting widely-used data, providing both oil and gas companies and farmers with detailed information about the distribution of carbon dioxide and how it can affect crop health.

In an analysis of the best available Earth systems models, Northeastern researchers found that by the turn of the next century, 850 million people will feel the effects of declining runoff from the world's major rivers.

The Environmental Protection Agency said on Friday that it would eliminate its scientific research arm and begin firing hundreds of chemists, biologists, toxicologists and other scientists, after denying for months that it intended to do so. The move underscores how the Trump administration is forging ahead with efforts to slash the federal work force and dismantle federal agencies after the Supreme Court allowed these plans to proceed while legal challenges unfold. Government scientists have been particular targets of the administration’s large-scale layoffs.

Research in Chile suggests climate crisis makes eruptions more likely and explosive, and warns of Antarctica risk

Recent simulations using the Community Earth System Model (CESM) indicate that a tipping event of the Atlantic Meridional Overturning Circulation (AMOC) would cause Europe to cool by several degrees. This AMOC tipping event was found under constant pre-industrial greenhouse gas forcing, while global warming likely limits this AMOC-induced cooling response. Here, we quantify the European temperature responses under different AMOC regimes and climate change scenarios. A strongly reduced AMOC state and intermediate global warming (C, Representative Concentration Pathway 4.5) has a profound cooling effect on Northwestern Europe with more intense cold extremes. The largest temperature responses are found during the winter months and these responses are strongly influenced by the North Atlantic sea-ice extent. Enhanced North Atlantic storm track activity under an AMOC collapse results in substantially larger day-to-day temperature fluctuations. We conclude that the (far) future European temperatures are dependent o

I’m used to environmentalists and futurists writing about The Limits to Growth. I’m less used to seeing investment writers mention research that’s linked to The Limits of Growth. But that’s what Joachim Klement did in his daily newsletter recently. Of course, anyone who writes about Limits of Growth has to do all the usual disclaimers first. This is because the combination of the words “limits” and “growth” in the title produced a lot of critical responses, on a range from straight-up hatchet jobs which misrepresented the book, to people who didn’t appear to understand the systems dynamics model that sat behind it.

2023 set a number of alarming new records. The global mean temperature also rose to nearly 1.5 degrees Celsius above the preindustrial level, another record.A team led by the Alfred Wegener Institute puts forward a possible explanation for the rise in global mean temperature: our planet has become less reflective because certain types of clouds have declined. The work is published in the journal Science.

Microplastics have been found for the first time in human ovary follicular fluid, raising a new round of questions about the ubiquitous and toxic substances’ potential impact on women’s fertility. The new peer-reviewed research published in Ecotoxicology and Environmental Safety checked for microplastics in the follicular fluid of 18 women undergoing assisted reproductive treatment at a fertility clinic in Salerno, Italy, and detected them in 14.

Recent projections suggest that large geographical areas will soon experience heat and humidity exceeding limits for human thermoregulation. The survivability limits modeled in that research were based on laboratory studies suggesting that humans cannot effectively thermoregulate in wet bulb temperatures (Twb) above 26 to 31 °C, values considerably lower than the widely publicized theoretical threshold of 35 °C. The newly proposed empirical limits were derived from the Twb corresponding to the core temperature inflection point in participants exposed to stepped increases in air temperature or relative humidity in a climate-controlled chamber. Despite the increasing use of these thermal-step protocols, their validity has not been established. We used a humidity-step protocol to estimate the Twb threshold for core temperature inflection in 12 volunteers.

The ocean ecosystem is a vital component of the global carbon cycle, storing enough carbon to keep atmospheric CO2 considerably lower than it would otherwise be. However, this conception is based on simple models, neglecting the coupled land-ocean feedback. Using an interactive Earth system model, we show that the role ocean biology plays in controlling atmospheric CO2 is more complex than previously thought. Atmospheric CO2 in a new equilibrium state after the biological pump is shut down increases by more than 50% (163 ppm), lower than expected as approximately half the carbon lost from the ocean is adsorbed by the land. The abiotic ocean is less capable of taking up anthropogenic carbon due to the warmer climate, an absent biological surface pCO2 deficit and a higher Revelle factor. Prioritizing research on and preserving marine ecosystem functioning would be crucial to mitigate climate change and the risks associated with it.

Amid President Donald Trump’s attacks on government scientists and science funding, researchers are arranging rallies to “Stand Up for Science” in Washington, D.C., and nationwide on March 7

As of February 22, over twenty Stand Up for Science protests are scheduled for March 7 throughout the United States. The protests are being organized by fellow scientists who are concerned about the Trump administration’s feelings and actions towards science (see Robles-Gil, 2025 in Science), includ

US government stripping funds from domestic and overseas research amid warnings for health and public safety

En réponse au lancement de Deep Research par OpenAI, Hugging Face développe Open Deep Research, un agent IA open source créé en seulement 24 heures.