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We propose a new paradigm, as toxicology currently lacks the proper perspective. From the 1950s to the 1970s, at least one-third of all toxicological testing in the United States, including for chemicals and drugs, was misleading scientists, and this worldwide issue persists today. Moreover, petroleum-based waste and heavy metals have been discovered in pesticide and plasticizer formulations. These contaminations have now reached all forms of life. Widespread exposure to chemical mixtures promotes health and environmental risks. We discovered that pesticides have never undergone long-term testing on mammals in their full commercial formulations by regulatory authorities or the pesticide industry; instead, only their declared active ingredients have been assessed, contrary to environmental law recommendations. The ingredients of these formulations are not fully disclosed, yet the formulations are in general at least 1000 times more toxic at low environmentally relevant doses than the active ingredients alone u

Cette thèse explore le phénomène de l'éco-anxiété et ses liens avec différents facteurs sociodémographiques, psychologiques et comportementaux. Elle s'appuie sur un ensemble de sept études complémentaires. La première, de nature qualitative, visait à re-cueillir les vécus de personnes se reconnaissant comme éco-anxieuses. La deuxième a consisté en la création et la validation psycho-métrique d'une Échelle de Mesure de l'Eco-Anxiété (EMEA). Les deux éludes suivantes ont permis d'élaborer une échelle mesurant le coping environnemental et d'examiner ses liens avec l'éco-anxiété. La cinquième étude a évalué l'association entre l'éco-anxiété et plusieurs facteurs psychologiques : l'anxiété et la dé-pression générales, les affects environnementaux, le sentiment de connexion à la nature et l'exposition aux informations relatives à la crise écologique. Enfin, la dernière étude, de nature longitudinale, portait sur l'impact psychologique et comportemental de la participation à un atelier de la Fresque du C

Effective identification and assessment of various energy transition risks are essential for ensuring energy security. This study conducts a systematic review of the literature on energy transition risk assessment, with three principal objectives: ① establishing a standardized risk taxonomy, ② analyzing the characteristics of current assessment methodologies, and ③ identifying the priority research directions. First, energy transition risks are structured into two categories: implementation risks and consequential risks. Subsequently, assessment methodologies are categorized into five methodological groups: the indicator approach, probabilistic risk assessment approach, econometric approach, simulation approach, and hybrid approach.

Purpose Animal emissions account for nearly 60% of total greenhouse gas emissions from the livestock sector. To estimate these emissions, the Food and Agriculture Organization of the United Nations (FAO) developed a dedicated module within the Global Livestock Environmental Assessment Model (GLEAM). Although previous studies have explored selected inputs for specific animals and emission types, a comprehensive analysis of all 92 inputs (parameters and emission factors) had not been conducted. This study aimed to identify the most influential inputs affecting ruminant emissions in GLEAM.

This article examines the technocentric bias that characterizes climate mitigation literature, focusing on the reports of the IPCC's Working Group III. This bias stems from structural features of the scientific field that prioritizes innovation, leading to the overrepresentation of technological solutions in climate research. Funding mechanisms further reinforce this tendency by incentivizing collaboration with industrial R&D, creating a self-reinforcing loop in which scientific authority and industrial interests converge. The IPCC's institutional positioning—as a policy-relevant yet politically cautious body—amplifies this dynamic by favoring allegedly “cost-effective” technological pathways that lack practical feasibility.

Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. It originates principally from the degradation of nonylphenol ethoxylates which are widely used as industrial surfactants. Nonylphenol ethoxylates reach sewage treatment works in substantial quantities where they biodegrade into several by-products including nonylphenol. Due to its physical–chemical characteristics, such as low solubility and high hydrophobicity, nonylphenol accumulates in environmental compartments that are characterised by high organic content, typically sewage sludge and river sediments, where it persists.

Why is the Trump Administration trying to kill a small space science institute in New York City? Explanation begins with Galileo’s method of scientific inquiry and ends with the role of special interest money in the United States government. Galileo improved the telescope, allowing clearer observations of the planets and the Sun. Galileo differed from his peers, as he was unafraid to challenge authority. He claimed that the world should be understood based on observations, and he spoke directly to the public. He obtained philanthropic support for his observations and openly described the conclusion that Earth was not the center of the solar system – Earth revolved around the Sun.

Identifying the socio-economic drivers behind greenhouse gas emissions is crucial to design mitigation policies. Existing studies predominantly analyze short-term CO2 emissions from fossil fuels, neglecting long-term trends and other GHGs. We examine the drivers of all greenhouse gas emissions between 1820–2050 globally and regionally. The Industrial Revolution triggered sustained emission growth worldwide—initially through fossil fuel use in industrialized economies but also as a result of agricultural expansion and deforestation. Globally, technological innovation and energy mix changes prevented 31 (17–42) Gt CO2e emissions over two centuries. Yet these gains were dwarfed by 81 (64–97) Gt CO2e resulting from economic expansion, with regional drivers diverging sharply: population growth dominated in Latin America and Sub-Saharan Africa, while rising affluence was the main driver of emissions elsewhere. Meeting climate targets now requires the carbon intensity of GDP to decline 3 times faster than the global

Contexte: Construire une protection sociale-écologique pour une transition juste […] Nos régimes de production et de consommation déstabilisent profondément la biosphère depuis des décennies, exacerbant des vulnérabilités existantes et causant de nouveaux risques qui menacent de plus en plus la stabilité sociale et politique partout sur la planète. Ces risques, qualifiés de risques sociaux-écologiques, sont de deux types: Les risques de transformation biophysique sont liés aux effets sociaux induits par les événements extrêmes (ex.: inondations, canicules, pandémies) et les événements à évolution lente (ex.: montée du niveau des mers) résultant de la déstabilisation anthropique de la biosphère. Les risques de transition sociotechnique sont liés aux effets sociaux des réponses aux risques de transformation biophysique. Ils couvrent les effets directs des politiques environnementales (ex.: mise en place de zones à faibles émissions, primes à la rénovation énergétique des logements, taxes carbone), ainsi que leu

Emerging infectious diseases, biodiversity loss, and anthropogenic environmental change are interconnected crises with massive social and ecological costs. In this Review, we discuss how pathogens and parasites are responding to global change, and the implications for pandemic prevention and biodiversity conservation. Ecological and evolutionary principles help to explain why both pandemics and wildlife die-offs are becoming more common; why land-use change and biodiversity loss are often followed by an increase in zoonotic and vector-borne diseases; and why some species, such as bats, host so many emerging pathogens. To prevent the next pandemic, scientists should focus on monitoring and limiting the spread of a handful of high-risk viruses, especially at key interfaces such as farms and live-animal markets. But to address the much broader set of infectious disease risks associated with the Anthropocene, decision-makers will need to develop comprehensive strategies that include pathogen surveillance across s

Abstract. We review how the international modelling community, encompassing integrated assessment models, global and regional Earth system and climate models, and impact models, has worked together over the past few decades to advance understanding of Earth system change and its impacts on society and the environment and thereby support international climate policy. We go on to recommend a number of priority research areas for the coming decade, a timescale that encompasses a number of newly starting international modelling activities, as well as the IPCC Seventh Assessment Report (AR7) and the second UNFCCC Global Stocktake. Progress in these priority areas will significantly advance our understanding of Earth system change and its impacts, increasing the quality and utility of science support to climate policy. We emphasize the need for continued improvement in our understanding of, and ability to simulate, the coupled Earth system and the impacts of Earth system change. There is an urgent need to investiga

Some narratives in international development hold that ending poverty and achieving good lives for all will require every country to reach the levels of GDP per capita that currently characterise high-income countries. However, this would require increasing total global output and resource use several times over, dramatically exacerbating ecological breakdown. Furthermore, universal convergence along these lines is unlikely within the imperialist structure of the existing world economy. Here we demonstrate that this dilemma can be resolved with a different approach, rooted in recent needs-based analyses of poverty and development. Strategies for development should not pursue capitalist growth and increased aggregate production as such, but should rather increase the specific forms of production that are necessary to improve capabilities and meet human needs at a high standard, while ensuring universal access to key goods and services through public provisioning and decommodification. At the same time, in high

Under current emission trajectories, temporarily overshooting the Paris global warming limit of 1.5 °C is a distinct possibility. Permanently exceeding this limit would substantially increase the probability of triggering climate tipping elements. Here, we investigate the tipping risks associated with several policy-relevant future emission scenarios, using a stylised Earth system model of four interconnected climate tipping elements.

Figure TS.15 | Contribution to (a) effective radiative forcing (ERF) and (b) global surface temperature change from component emissions for1750–2019based on Coupled Model Intercomparison Project Phase 6 (CMIP6) models and (c) net aerosol ERF for 1750–2014 from different lines of evidence.

Evidence shows a continuing increase in the frequency and severity of global heatwaves1,2, raising concerns about the future impacts of climate change and the associated socioeconomic costs3,4. Here we develop a disaster footprint analytical framework by integrating climate, epidemiological and hybrid input–output and computable general equilibrium global trade models to estimate the midcentury socioeconomic impacts of heat stress. We consider health costs related to heat exposure, the value of heat-induced labour productivity loss and indirect losses due to economic disruptions cascading through supply chains. Here we show that the global annual incremental gross domestic product loss increases exponentially from 0.03 ± 0.01 (SSP 245)–0.05 ± 0.03 (SSP 585) percentage points during 2030–2040 to 0.05 ± 0.01–0.15 ± 0.04 percentage points during 2050–2060. By 2060, the expected global economic losses reach a total of 0.6–4.6% with losses attributed to health loss (37–45%), labour productivity loss (18–37%) and i

Anthropogenic emissions drive global-scale warming yet the temperature increase relative to pre-industrial levels is uncertain. Using 300 years of ocean mixed-layer temperature records preserved in sclerosponge carbonate skeletons, we demonstrate that industrial-era warming began in the mid-1860s, more than 80 years earlier than instrumental sea surface temperature records. The Sr/Ca palaeothermometer was calibrated against ‘modern’ (post-1963) highly correlated (R2 = 0.91) instrumental records of global sea surface temperatures, with the pre-industrial defined by nearly constant (<±0.1 °C) temperatures from 1700 to the early 1860s. Increasing ocean and land-air temperatures overlap until the late twentieth century, when the land began warming at nearly twice the rate of the surface oceans. Hotter land temperatures, together with the earlier onset of industrial-era warming, indicate that global warming was already 1.7 ± 0.1 °C above pre-industrial levels by 2020. Our result is 0.5 °C higher than IPCC estim

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Produite à partir de cellules en prolifération dans des bioréacteurs, la « viande de culture » est présentée comme une solution à la demande grandissante en protéines animales sans certains des inconvénients de l’élevage. Ce premier article décrit les qualités sanitaires, nutritionnelles et organoleptiques à partir des connaissances disponibles. Un point d’attention concerne la composition et le coût du milieu de culture, notamment concernant les alternatives au sérum de veau fœtal. L’innocuité de ce nouvel aliment fait débat entre les scientifiques, avec, d’un côté ceux qui affirment que la consommation de la « viande de culture » sera plus sûre que celle de la viande conventionnelle, et ceux qui, au contraire, sont plus prudents, considérant que les risques sanitaires ne sont pas entièrement connus.

Daniel P. Aldrich (born 1974) is an academic in the fields of political science, public policy and Asian studies. He is currently full professor of political science and public policy at Northeastern University.[1] Aldrich has held several Fulbright fellowships, including a Fulbright Distinguished Chair in Applied Public Policy (Democratic Resilience) at Flinders University in Australia in 2023,[2] a Fulbright Specialist[3] in Trinidad-Tobago in 2018, a Fulbright research fellowship at the University of Tokyo's Economic's Department for the 2012–2013 academic year, and a IIE Fulbright Dissertation Fellowship in Tokyo in 2002–2003. His research, prompted in part by his own family's experience of Hurricane Katrina,[4] explores how communities around the world respond to and recover from disaster.

Les forêts françaises couvrent 31% du territoire métropolitain. Elles contribuent de multiples façons au bienêtre humain (production de bois, purification de l’air et de l’eau, maintien des sols, habitat pour la biodiversité, alimentation, santé, activités récréatives, etc.) et participent aux Objectifs de Développement Durable fixés par l’ONU. En particulier, la France s’étant engagée à atteindre la neutralité carbone dès 2050, le rôle de puits et de stockage de carbone des forêts est considéré comme un élément majeur de sa Stratégie Nationale Bas Carbone (SNBC). Depuis quelques années, les forêts françaises, dont la surface n’avait cessé de croître depuis plus d’un siècle, connaissent, de façon inquiétante, une diminution de productivité, des dépérissements massifs et un risque incendie accru. Le changement climatique en cours met ainsi en péril les ressources forestières et leur contribution attendue pour préserver la biodiversité, favoriser le développement rural et la bioéconomie, renforcer la production